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Methodological implications of simultaneous solid-phase peptide synthesis: a comparison of active esters


Abstract Simultaneous competition and comparison methods have been used to compare the activities of a wide variety of reactive esters for solid phase custom peptide synthesis. The results generally conform to expectations from the literature; the most active being dinitrophenyl esters. Pentafluorophenyl esters provide the most suitable selection for routine use.
 Variability in infants' brain responses elicited under the same mnemonic condition, however, has not been previously examined. The present report undertook two separate analyses in order to examine two kinds of variability: variability in the brain's response to a stimulus over time as a function of stimulus repetition, and variability in the brain's response between subjects as a function of the total number of trials completed in an ERP session. There were three major findings: (a) the mid-latency negative component (Nc) and long-latency slow wave (SW) were found to dissociate cognitive processes associated with familiarity from processes associated with stimulus repetition,
The critically acclaimed laboratory standard for more than forty years, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features* Solid-phase  custom peptide synthesis Applications of peptides for structural and biological studies Characterization of synthetic peptides
custom peptide synthesis
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